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ST096085 Flupirtine maleate


Formula: C19H21FN4O6

MW: 420.4

CAS: 75507-68-5

MDL NUMBER: MFCD00941415

Smiles: OC(=O)/C=C/C(O)=O.CCOC(=O)Nc1ccc(NCc2ccc(F)cc2)nc1N

THERAPEUTIC CATEGORY: Flupirtine, an aminopyridine is a centrally acting nonopioid analgesic. It is available in Europe since 1984 and sold mainly under the names Katadolon, Trancolong and Metanor. It is unique as an non-opioid, non-NSAID, non-steroidal analgesic.

ACCEPTORS: 6

DONORS: 6

ROTATION BONDS: 7

N+O: 10

Chiral Centers: 0

LogP: 3.19

LogS: -4.18

LIPINSKI: 3

Synonyms: ethyl 2-amino-6-[(4-fluorobenzyl)amino]pyridine-3-carbamate compound with maleic acid (1:1);FLUPIRTINE MALEATE;2-AMINO-6-[[(4-FLUOROPHENYL)METHYL]AMINO]-3-PYRIDINYL]-CARBAMIC ACID, ETHYL ESTER MALEATE;Flupirtinemaleatelupirtine;Ethyl-2-amino-6-[(4-fluorbenzyl)amino]pyridin-3-carbamat, Verbindung mit Maleinsure (1:1);Keiton;Ketadolon;N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamicacidethylestermaleate

CAS:75507-68-5

MF:C15H17FN4O2.C4H4O4

MW:420.4

EINECS:278-225-0

Product Categories:Other Potassium channel modulators;APIS Flupirtine maleate

Chemical Properties: storage temp. 2-8C

Safety Information: Safety Statements 22-24/25 Flupirtine maleate

Usage And Synthesis: Biological ActivityNon-opioid analgesic with muscle relaxant properties. Activates K + channels and indirectly antagonizes NMDA receptors. Exhibits neuroprotective actions in a model of cerebral ischemia in mice and reduces apoptosis and necrosis induced by noxious stimuli. Flupirtine maleate

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ST096084 Nateglinide

ST096084 Nateglinide

Formula: C19H27NO3MW: 317.43CAS: 105816-04-4MDL NUMBER: MFCD00875706Smiles: CC(C)C1CCC(CC1)C(=O)NC(C..
ST096085 Flupirtine maleate

ST096085 Flupirtine maleate

Formula: C19H21FN4O6MW: 420.4CAS: 75507-68-5MDL NUMBER: MFCD00941415Smiles: OC(=O)/C=C/C(O)=O.CCOC(=..
ST096086 Flibanserin

ST096086 Flibanserin

Formula: C20H21F3N4OMW: 390.41CAS: 167933-07-5MDL NUMBER: MFCD00918402Smiles: FC(F)(F)c1ccc(cc1)N1CC..